Merck Millipore Audited

Within the Merck Millipore division, we are working with our customers to develop innovative solutions for the research, development and production of biopharmaceuticals and biotech processes worldwide.

Lab Solutions

In 2013, the Lab Solutions business unit developed the EZ-product family. It comprises the EZ-Fit™ Manifold, the EZ-Pak® Dispenser Curve, the EZ-Stream™ Pump, and the EZ-Fluo™ Rapid Detection System. The aim of these products is to streamline the bioburden analysis workflow. The EZ-Fit™ Manifold makes laboratory filtration easier thanks to its unique design that permits assembly and disassembly without tools, access to all internal areas for easy cleaning, and a low profile to increase operator comfort. Different filtration heads, all with quick-fit connections, make the manifold compatible with disposable filtration devices, stainless steel and glass funnels. The EZ-Pak® Dispenser Curve provides high-speed sterile membrane dispensing with no-touch operation. With the efficient EZ-Stream™ Pump, filtered fluids flow directly through the pump to waste, eliminating the need for intermediate waste containers. The pump is designed for quiet operation, and the vacuum level is compliant with regulatory standards. The EZ-product family is complemented by the EZ-Fluo™ Rapid Detection System, an easy-to-use, non-destructive, fluorescent staining-based system for rapid detection and quantification of microbial contamination in filterable samples.

Process Solutions

The Process Solutions business unit is also continuously working to develop new products. For instance, Clarisolve® Depth Filters, used in cell culture processing, were launched in September 2013. Their greater volumetric capacity and reduced turbidity over currently available depth filters significantly improve the clarification of pretreated feed streams. In addition, the Clarisolve® system does not require a secondary stage of clarification, while eliminating the need for centrifugation and reducing the pre-use flushing volume by up to 93%. This lowers the environmental burden and helps customers to improve overall process economics. In December 2013, Clarisolve® Depth Filters received an Innovation Award from “Pharmaceutical Manufacturing Magazine”, a U.S. trade publication.

Bioscience

The Bioscience business unit is a prime example of innovation. For instance, Merck Millipore has developed, among others, the Muse™ Cell Analyzer, which is one of the world’s leading analytical devices. The Muse™ Cell Analyzer provides real-time, multidimensional information on cell populations. This semistationary flow cytometer enables faster, more accurate decision-making based on greater insight into cell health. As a result, the speed and efficiency of cell analysis are enhanced. In 2013, the Muse™ Cell Analyzer was presented with the renowned silver R&D Magazine 100 Award (Stevie Award), as well as the Good Design Award of the Chicago Athenaeum: Museum of Architecture and Design.